BDBM50337322 5-(1-(2,3-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682354

SMILES Clc1cccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)c1Cl

InChI Key InChIKey=WEGHHPFXCHFJFR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337322   

TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337322(5-(1-(2,3-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  15nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337322(5-(1-(2,3-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  48nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337322(5-(1-(2,3-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  66nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337322(5-(1-(2,3-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  2.03E+4nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337322(5-(1-(2,3-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  6.76E+4nMAssay Description:Inhibition of Pak4 after 1 hr using biotinylated L15 peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed