BDBM50337323 5-(1-(3,5-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682356

SMILES Clc1cc(Cl)cc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)c1

InChI Key InChIKey=YPLADSZZPCZLET-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337323   

TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337323(5-(1-(3,5-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  28nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337323(5-(1-(3,5-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  41nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337323(5-(1-(3,5-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  240nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337323(5-(1-(3,5-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi: >915nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337323(5-(1-(3,5-dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1...)
Affinity DataKi:  4.15E+4nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed