BDBM50337331 1-(4-(4-(5-methyl-1,3,4-thiadiazol-2-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)piperazin-1-yl)-2-phenylethanone::CHEMBL1682361

SMILES Cc1nnc(Nc2nc(nn3cccc23)N2CCN(CC2)C(=O)Cc2ccccc2)s1

InChI Key InChIKey=KINQBFBTEKKXKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337331   

TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337331(1-(4-(4-(5-methyl-1,3,4-thiadiazol-2-ylamino)pyrro...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337331(1-(4-(4-(5-methyl-1,3,4-thiadiazol-2-ylamino)pyrro...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of JAK3 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed