BDBM50337332 2-(4-chlorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)piperazin-1-yl)ethanone::CHEMBL1682386

SMILES Cc1cc(Nc2nc(N3CCN(C(=O)Cc4ccc(Cl)cc4)CC3)nn3cccc23)[nH]n1

InChI Key InChIKey=PEWNLAZCWLHUMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337332   

TargetTyrosine-protein kinase JAK2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50337332BDBM50337332(2-(4-chlorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed