BDBM50337337 2-(4-methoxyphenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)piperazin-1-yl)ethanone::CHEMBL1682385

SMILES COc1ccc(CC(=O)N2CCN(CC2)c2nc(Nc3cc(C)n[nH]3)c3cccn3n2)cc1

InChI Key InChIKey=VGBCROSCXXBWEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337337   

TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337337(2-(4-methoxyphenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed