BDBM50337352 CHEMBL1682370::N,N-dimethyl-4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)piperazine-1-carboxamide

SMILES CN(C)C(=O)N1CCN(CC1)c1nc(Nc2cc(C)n[nH]2)c2cccn2n1

InChI Key InChIKey=PCXPNJOIYHRNLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337352   

TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337352(N,N-dimethyl-4-(4-(5-methyl-1H-pyrazol-3-ylamino)p...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed