BDBM50337558 (R)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(pyrimidin-4-yl)pyridin-2(1H)-one::CHEMBL1682852

SMILES COc1ccccc1[C@@H]1CN(CCO1)c1cc(cc(=O)n1C)-c1ccncn1

InChI Key InChIKey=UXIBAVJUVOXYPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337558   

TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337558((R)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50: 62.8nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337558((R)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed