BDBM50337643 1-benzyl-3-isopropyl-1-(3-((4-methoxyphenyl)ethynyl)benzyl)urea::CHEMBL1683200

SMILES COc1ccc(cc1)C#Cc1cccc(CN(Cc2ccccc2)C(=O)NC(C)C)c1

InChI Key InChIKey=HFTATOXSZLPRMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337643   

TargetProstaglandin E synthase(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337643(1-benzyl-3-isopropyl-1-(3-((4-methoxyphenyl)ethyny...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of mPGES1 in IL1-beta treated human A549 cell microsome assessed as inhibition of PGE2 production after 1 min in presence of 50% FBSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337643(1-benzyl-3-isopropyl-1-(3-((4-methoxyphenyl)ethyny...)
Affinity DataIC50: 72nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed