BDBM50337650 3-isopropyl-1-(3-methoxybenzyl)-1-(3-(phenylethynyl)benzyl)urea::CHEMBL1683207

SMILES COc1cccc(CN(Cc2cccc(c2)C#Cc2ccccc2)C(=O)NC(C)C)c1

InChI Key InChIKey=WCGLXHAPTRXOBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337650   

TargetProstaglandin E synthase(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337650(3-isopropyl-1-(3-methoxybenzyl)-1-(3-(phenylethyny...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of mPGES1 in IL1-beta treated human A549 cell microsome assessed as inhibition of PGE2 production after 1 min in presence of 50% FBSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50337650(3-isopropyl-1-(3-methoxybenzyl)-1-(3-(phenylethyny...)
Affinity DataIC50: 46nMAssay Description:Inhibition of mPGES1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed