BDBM50337847 (1-(naphthalen-2-yl)cyclohexyl)methanamine::CHEMBL1683900::US10562878, Compound 33

SMILES NCC1(CCCCC1)c1ccc2ccccc2c1

InChI Key InChIKey=SAARGPSTPXUSIL-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50337847   

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 232nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 305nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 305nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 232nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 948nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337847((1-(naphthalen-2-yl)cyclohexyl)methanamine | CHEMB...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent