BDBM50338199 5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine::5-(2-morpholino-7-(pyridin-3-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amine::CHEMBL1684986

SMILES Nc1ncc(cn1)-c1nc(nc2N(CCc12)c1cccnc1)N1CCOCC1

InChI Key InChIKey=WZVLQVVHYKFKAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50338199   

LigandPNGBDBM50338199(5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha expressed in baculovirus preincubated for 20 mins followed by addition of phosphorylate phosphatidylinosi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2017
Entry Details Article
PubMed
LigandPNGBDBM50338199(5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50338199(5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using phosphatidylinositol 4,5-bisphosphate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50338199(5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by adapta universal kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed