BDBM50338201 1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yloxy)-2-chlorophenyl)-3-ethylurea::CHEMBL1681932

SMILES CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1Cl

InChI Key InChIKey=BJHCYTJNPVGSBZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50338201   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 183nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 513nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 622nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50338201(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed