BDBM50338329 CHEMBL1681798::N-(2-{3-[(5-Chlorothiophen-2-yl)carbonylamino]methyl}phenyl)-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide

SMILES C[N@@]1CCc2c(sc(n2)C(=O)Nc3ccccc3CNC(=O)c4ccc(s4)Cl)C1

InChI Key InChIKey=LMUFNFLXBDOGET-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338329   

TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338329(N-(2-{3-[(5-Chlorothiophen-2-yl)carbonylamino]meth...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338329(N-(2-{3-[(5-Chlorothiophen-2-yl)carbonylamino]meth...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human factor 10a using S-2222 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)