BDBM50338440 CHEMBL1682974::trans-N-(4-((S)-1-amino-2-oxo-2-(thiazolidin-3-yl)ethyl)cyclohexyl)-4-(trifluoromethoxy)benzamide

SMILES N[C@@H]([C@H]1CC[C@@H](CC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)N1CCSC1

InChI Key InChIKey=BXWYQMPOVCJLIS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338440   

TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(trans-N-(4-((S)-1-amino-2-oxo-2-(thiazolidin-3-yl)...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(trans-N-(4-((S)-1-amino-2-oxo-2-(thiazolidin-3-yl)...)
Affinity DataIC50: 170nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(trans-N-(4-((S)-1-amino-2-oxo-2-(thiazolidin-3-yl)...)
Affinity DataIC50: 690nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(trans-N-(4-((S)-1-amino-2-oxo-2-(thiazolidin-3-yl)...)
Affinity DataIC50: 33nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(trans-N-(4-((S)-1-amino-2-oxo-2-(thiazolidin-3-yl)...)
Affinity DataIC50: 570nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed