BDBM50338522 5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(trifluoromethyl)benzyl)-1H-imidazole-4-carboxamide::CHEMBL1683577

SMILES Cc1c(ncn1Cc1cccc(c1)C(F)(F)F)C(=O)Nc1ccn(C)n1

InChI Key InChIKey=DUTKICDSXNUMBM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50338522   

TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 11.8nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338522(5-methyl-N-(1-methyl-1H-pyrazol-3-yl)-1-(3-(triflu...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of rat SCD1 by rat microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed