BDBM50339038 CHEMBL1688247::N-((1H-pyrazol-4-yl)methyl)-3-(5-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)pyridin-2-amine

SMILES FC(F)(F)c1cccc(c1)-c1nnc([nH]1)-c1cccnc1NCc1cn[nH]c1

InChI Key InChIKey=DDNYJQBAUGAKMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339038   

LigandPNGBDBM50339038(N-((1H-pyrazol-4-yl)methyl)-3-(5-(3-(trifluorometh...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 expressed HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339038(N-((1H-pyrazol-4-yl)methyl)-3-(5-(3-(trifluorometh...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR-2 kinase assessed as phosphorylated level of pGAT-biotin peptide preincubated for 5 to 10 mins before addition of substrate measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed