BDBM50339040 3-(5-(benzo[d][1,3]dioxol-5-yl)-4H-1,2,4-triazol-3-yl)-N-(pyridin-4-ylmethyl)pyridin-2-amine::CHEMBL1688249

SMILES C(Nc1ncccc1-c1nnc([nH]1)-c1ccc2OCOc2c1)c1ccncc1

InChI Key InChIKey=ABGLJSGHTCBIRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339040   

LigandPNGBDBM50339040(3-(5-(benzo[d][1,3]dioxol-5-yl)-4H-1,2,4-triazol-3...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of VEGFR-2 kinase assessed as phosphorylated level of pGAT-biotin peptide preincubated for 5 to 10 mins before addition of substrate measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339040(3-(5-(benzo[d][1,3]dioxol-5-yl)-4H-1,2,4-triazol-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 expressed HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed