BDBM50339055 CHEMBL1688344::N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-5-(2-(pyridin-4-ylmethylamino)pyridin-3-yl)-1,3,4-oxadiazol-2-amine

SMILES FC1(F)Oc2ccc(Nc3nnc(o3)-c3cccnc3NCc3ccncc3)cc2O1

InChI Key InChIKey=UUWCZQYGBSUBRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339055   

LigandPNGBDBM50339055(N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-5-(2-(pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 expressed HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339055(N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-5-(2-(pyr...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of VEGFR-2 kinase assessed as phosphorylated level of pGAT-biotin peptide preincubated for 5 to 10 mins before addition of substrate measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed