BDBM50339058 7-cyclobutyl-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-4-amine::CHEMBL1688358

SMILES Nc1ncnn2c(nc(-c3ccc4ccc(nc4c3)-c3ccccc3)c12)C1CCC1

InChI Key InChIKey=BHTAGACZYNRXNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339058   

LigandPNGBDBM50339058(7-cyclobutyl-5-(2-phenylquinolin-7-yl)imidazo[1,5-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human IGF1R in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50339058(7-cyclobutyl-5-(2-phenylquinolin-7-yl)imidazo[1,5-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of auto-phosphorylation of human IGF1R expressed in mouse NIH-3T3 cells after 2 hrs by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed