BDBM50339060 CHEMBL1688359::cis-3-(4-amino-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-7-yl)-1-methylcyclobutanol

SMILES C[C@@]1(O)C[C@@H](C1)c1nc(-c2ccc3ccc(nc3c2)-c2ccccc2)c2c(N)ncnn12

InChI Key InChIKey=FILMJNHPVCSZTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339060   

LigandPNGBDBM50339060(cis-3-(4-amino-5-(2-phenylquinolin-7-yl)imidazo[1,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of auto-phosphorylation of human IGF1R expressed in mouse NIH-3T3 cells after 2 hrs by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339060(cis-3-(4-amino-5-(2-phenylquinolin-7-yl)imidazo[1,...)
Affinity DataIC50: 700nMAssay Description:Inhibition of auto-phosphorylation of human IR expressed in human HepG2 cells after 2 hrs by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed