BDBM50339244 2-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoyl-7-(3-guanidinopropyl)-2,18-dimethyl-6,9,12,15-tetraoxo-5,8,11,14-tetraazanonadecan-16-yl)thiazole-4-carboxamide::CHEMBL1689560

SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-c1csc(-[#7])n1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#7])=O

InChI Key InChIKey=YZFOJWPYQXUEIN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339244   

TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339244(2-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  142nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339244(2-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  1.77E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed