BDBM50339351 (+/-)-cis-3-(4-Chlorophenyl)-3-(4-hydroxycyclopent-2-enyloxy)-2-(4-methylbenzyl)isoindolin-1-one::CHEMBL1688256::US8618158, NU8295

SMILES Cc1ccc(CN2C(=O)c3ccccc3C2(O[C@@H]2C[C@H](O)C=C2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=GQWCFDLMBXJXGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339351   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339351(CHEMBL1688256 | US8618158, NU8295 | (+/-)-cis-3-(4...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339351(CHEMBL1688256 | US8618158, NU8295 | (+/-)-cis-3-(4...)
Affinity DataIC50: 1.40E+3nMT: 2°CAssay Description:Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
US Patent