BDBM50339521 (+/-)-6-Ethyl-6-[4-[(4-fluorophenylthio)methyl]phenyl]-6,7-dihydrobenzo[b]pyrrolo[1,2-d][1,4]oxazepin-7-one::CHEMBL1688504

SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc(CSc2ccc(F)cc2)cc1

InChI Key InChIKey=UEKVYQRCICRDNH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50339521   

TargetAdenosine kinase(Human)
Universita` Di Siena

Curated by ChEMBL
LigandPNGBDBM50339521((+/-)-6-Ethyl-6-[4-[(4-fluorophenylthio)methyl]phe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
2-Universit£

Curated by ChEMBL
LigandPNGBDBM50339521((+/-)-6-Ethyl-6-[4-[(4-fluorophenylthio)methyl]phe...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
2-Universit£

Curated by ChEMBL
LigandPNGBDBM50339521((+/-)-6-Ethyl-6-[4-[(4-fluorophenylthio)methyl]phe...)
Affinity DataIC50: 250nMAssay Description:Inhibition of HIV1 wild type reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
2-Universit£

Curated by ChEMBL
LigandPNGBDBM50339521((+/-)-6-Ethyl-6-[4-[(4-fluorophenylthio)methyl]phe...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase V179D mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
2-Universit£

Curated by ChEMBL
LigandPNGBDBM50339521((+/-)-6-Ethyl-6-[4-[(4-fluorophenylthio)methyl]phe...)
Affinity DataIC50: 3.35E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed