BDBM50339754 CHEMBL1689135::[4-Chloro-2-({(3S)-4-[(4-chlorophenyl)acetyl]-3-methylpiperazin-1-yl}methyl)phenyl]acetic Acid

SMILES C[C@H]1CN(Cc2cc(Cl)ccc2CC(O)=O)CCN1C(=O)Cc1ccc(Cl)cc1

InChI Key InChIKey=UTYMAGFCZOUQSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339754   

TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339754([4-Chloro-2-({(3S)-4-[(4-chlorophenyl)acetyl]-3-me...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339754([4-Chloro-2-({(3S)-4-[(4-chlorophenyl)acetyl]-3-me...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed