BDBM50339769 2-(2-((4-(benzylsulfonyl)-1,4-diazepan-1-yl)methyl)-4-chlorophenoxy)acetic acid::CHEMBL1689115

SMILES OC(=O)COc1ccc(Cl)cc1CN1CCCN(CC1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=FSYMRBYJPOBPII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339769   

TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339769(2-(2-((4-(benzylsulfonyl)-1,4-diazepan-1-yl)methyl...)
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339769(2-(2-((4-(benzylsulfonyl)-1,4-diazepan-1-yl)methyl...)
Affinity DataIC50: 89nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed