BDBM50339807 CHEMBL1689277::N-[(3beta,18beta,20beta)-3-(Acetoxy)-11-oxo-30-norolean-12-en-20-yl]-N'-[(trifluoromethyl)sulfonyl]urea

SMILES CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2C(=O)C=C2[C@@H]4C[C@](C)(CC[C@]4(C)CC[C@@]32C)NC(=O)NS(=O)(=O)C(F)(F)F)C1(C)C

InChI Key InChIKey=WAYRKSNQTDOQAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339807   

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
University of Technology

Curated by ChEMBL
LigandPNGBDBM50339807(N-[(3beta,18beta,20beta)-3-(Acetoxy)-11-oxo-30-nor...)
Affinity DataIC50: 194nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Technology

Curated by ChEMBL
LigandPNGBDBM50339807(N-[(3beta,18beta,20beta)-3-(Acetoxy)-11-oxo-30-nor...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed