BDBM50339875 (S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)ethanol::CHEMBL1761457

SMILES Cc1c([C@@H]2CCCN(C2)c2nccc(n2)-c2cc3ccccc3s2)c2cccnc2n1CCO

InChI Key InChIKey=RXVRDGZXPYUYJA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50339875   

TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50: 53nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed