BDBM50339911 CHEMBL1761652::trans-rac-2-(1-benzyl-7-chloro-5-(2-chlorophenyl)-2-oxo-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)acetic acid

SMILES OC(=O)CN1C[C@H](c2ccccc2Cl)c2cc(Cl)ccc2[C@@H](Cc2ccccc2)C1=O

InChI Key InChIKey=NNUVTLUSHGZXSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339911   

TargetSqualene synthase(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339911(trans-rac-2-(1-benzyl-7-chloro-5-(2-chlorophenyl)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed