BDBM50339916 CHEMBL1761660::trans-rac-7-chloro-1-isobutyl-5-(2-methoxyphenyl)-3-(2-oxo-2-(piperidin-1-yl)ethyl)-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one

SMILES COc1ccccc1[C@H]1CN(CC(=O)N2CCCCC2)C(=O)[C@H](CC(C)C)c2ccc(Cl)cc12

InChI Key InChIKey=VMCQFERNKVBDRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339916   

TargetSqualene synthase(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339916(trans-rac-7-chloro-1-isobutyl-5-(2-methoxyphenyl)-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed