BDBM50339923 CHEMBL1761655::trans-rac-2-(5-(2-methoxyphenyl)-7-chloro-1-isobutyl-2-oxo-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)acetic acid

SMILES COc1ccccc1[C@H]1CN(CC(O)=O)C(=O)[C@H](CC(C)C)c2ccc(Cl)cc12

InChI Key InChIKey=YBPYETHENAODPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339923   

TargetSqualene synthase(Human)
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339923(trans-rac-2-(5-(2-methoxyphenyl)-7-chloro-1-isobut...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed