BDBM50340028 4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2,4-triazol-3-yl)methyl)-6-(trifluoromethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1762497

SMILES CCCn1c(CCc2ccc(Cl)cc2)nnc1CN1C(=O)COc2ccc(cc12)C(F)(F)F

InChI Key InChIKey=PXHKXNLUZHNGBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340028   

TargetSodium/glucose cotransporter 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340028(4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2,4-triazo...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50340028(4-((5-(4-chlorophenethyl)-4-propyl-4H-1,2,4-triazo...)
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed