BDBM50340303 (S)-N-(2-ethoxyethyl)-N-(2-hydroxy-3-(9-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,9-diazaspiro[5.5]undecan-2-yl)propyl)-2,6-dimethylbenzenesulfonamide::CHEMBL1760758

SMILES CCOCCN(C[C@@H](O)CN1CCCC2(CCN(CC2)c2ncnc3[nH]cc(C)c23)C1)S(=O)(=O)c1c(C)cccc1C

InChI Key InChIKey=ODFPLSCCVBAEFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340303   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340303((S)-N-(2-ethoxyethyl)-N-(2-hydroxy-3-(9-(5-methyl-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340303((S)-N-(2-ethoxyethyl)-N-(2-hydroxy-3-(9-(5-methyl-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed