BDBM50340305 CHEMBL1760760::N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(7-(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-2,7-diazaspiro[4.4]nonan-2-yl)propyl)-2,6-dimethylbenzenesulfonamide

SMILES CCOCCN(C[C@@H](O)CN1CCC2(CCN(C2)c2ncnc3n[nH]c(C)c23)C1)S(=O)(=O)c1c(C)cccc1C

InChI Key InChIKey=GHARCVPTJMBSSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340305   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340305(N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(7-(3-methyl...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340305(N-(2-ethoxyethyl)-N-((2S)-2-hydroxy-3-(7-(3-methyl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed