BDBM50340309 (+/-)-N-(3-(2-(6-amino-5-cyclopropylpyrimidin-4-yl)-2,7-diazaspiro[4.5]decan-7-yl)-2-hydroxypropyl)-N-(2-ethoxyethyl)-2,6-dimethylbenzenesulfonamide::CHEMBL1760764

SMILES CCOCCN(C[C@@H](O)CN1CCCC2(CCN(C2)c2ncnc(N)c2C2CC2)C1)S(=O)(=O)c1c(C)cccc1C

InChI Key InChIKey=BDOPKJRMCXOBQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340309   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340309((+/-)-N-(3-(2-(6-amino-5-cyclopropylpyrimidin-4-yl...)
Affinity DataIC50: 470nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340309((+/-)-N-(3-(2-(6-amino-5-cyclopropylpyrimidin-4-yl...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed