BDBM50340731 CHEMBL1762569::N,N,5,7-Tetramethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-2-amine::US8829009, 1.1(2)

SMILES CN(C)c1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1

InChI Key InChIKey=YBQJHPSFWWRXNX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340731   

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50340731(CHEMBL1762569 | US8829009, 1.1(2) | N,N,5,7-Tetram...)
Affinity DataIC50: 1.18E+3nMAssay Description:Determination of antagonistic activity of compounds of general formula 1 towards 5-HT6 receptors. Compounds of general formula 1 were tested for thei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50340731(CHEMBL1762569 | US8829009, 1.1(2) | N,N,5,7-Tetram...)
Affinity DataKi:  14.5nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production after 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed