BDBM50340899 (4-amino-2-(pyridin-2-ylamino)thiazol-5-yl)(2-methoxyphenyl)methanone::CHEMBL1761788

SMILES COc1ccccc1C(=O)c1sc(Nc2ccccn2)nc1N

InChI Key InChIKey=MAUHUPWBMYAXPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340899   

TargetCyclin-dependent kinase 5 activator 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50340899((4-amino-2-(pyridin-2-ylamino)thiazol-5-yl)(2-meth...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into peptide PKTPKKAKKL substrate after 45 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed