BDBM50340931 1-(4-((6,7-dimethoxyquinazolin-4-yl)(methyl)amino)phenyl)-3-(4-methoxyphenyl)urea::CHEMBL1761935

SMILES COc1ccc(NC(=O)Nc2ccc(cc2)N(C)c2ncnc3cc(OC)c(OC)cc23)cc1

InChI Key InChIKey=OEYVCQWJXHIRAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340931   

TargetEpidermal growth factor receptor(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50340931(1-(4-((6,7-dimethoxyquinazolin-4-yl)(methyl)amino)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50340931(1-(4-((6,7-dimethoxyquinazolin-4-yl)(methyl)amino)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed