BDBM50340941 1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-para-tolylurea::CHEMBL1761941

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(C)cc4)cc3)c2cc1OC

InChI Key InChIKey=FKGPIUWVQHERRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340941   

TargetVascular endothelial growth factor receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50340941(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-pa...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50340941(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-pa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed