BDBM50341076 (3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxybenzyl)piperazin-1-yl)methanone::CHEMBL1760339

SMILES COc1ccccc1CN1CCN(CC1)C(=O)c1cc(n[nH]1)-c1ccc(Cl)cc1

InChI Key InChIKey=UUOUKHVFSLUAIM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50341076   

TargetNeuromedin-K receptor(Human)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341076((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyb...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341076((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyb...)
Affinity DataKi:  490nMAssay Description:Displacement [3H]SB-222200 from of human recombinant NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341076((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyb...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity to human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Rat)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341076((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyb...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity to rat NK3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341076((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyb...)
Affinity DataKi:  1.90E+4nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed