BDBM50341105 (4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(trifluoromethoxy)phenyl)-1H-pyrazol-5-yl)methanone::CHEMBL1760209

SMILES COc1ccccc1N1CCN(CC1)C(=O)c1cc(n[nH]1)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=XVJACFQXERAVKG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341105   

TargetNeuromedin-K receptor(Human)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341105((4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(trifluor...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Euroscreen

Curated by ChEMBL
LigandPNGBDBM50341105((4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(trifluor...)
Affinity DataKi:  310nMAssay Description:Displacement [3H]SB-222200 from of human recombinant NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed