BDBM50341187 CHEMBL1760900::N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-4-(3-(trifluoromethyl)phenyl)piperidine-1-carboxamide

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)N3CCC(CC3)c3cccc(c3)C(F)(F)F)sc12

InChI Key InChIKey=MCOQRPPGECKENM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341187   

TargetAdenosine receptor A1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341187(N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341187(N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human adenosine A2B receptor expressed in CHO cells assessed as decrease in cellular cAMP level after 20 to 25 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50341187(N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed