BDBM50341605 4-(2-Methoxyphenyl)ureido-2-phenylphthalazin-1(2H)-one::CHEMBL1766354

SMILES COc1ccccc1NC(=O)Nc1nn(-c2ccccc2)c(=O)c2ccccc12

InChI Key InChIKey=LICHQSKCILPIJB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341605   

TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341605(4-(2-Methoxyphenyl)ureido-2-phenylphthalazin-1(2H)...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP accumulation after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita` Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50341605(4-(2-Methoxyphenyl)ureido-2-phenylphthalazin-1(2H)...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed