BDBM50341661 (E)-3-(3-Amino-4-hydroxybenzylidene)chroman-4-one::CHEMBL1766561

SMILES Nc1cc(\C=C2/COc3ccccc3C2=O)ccc1O

InChI Key InChIKey=ZIHNBSAQKASXAJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341661   

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341661((E)-3-(3-Amino-4-hydroxybenzylidene)chroman-4-one ...)
Affinity DataIC50: 484nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341661((E)-3-(3-Amino-4-hydroxybenzylidene)chroman-4-one ...)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341661((E)-3-(3-Amino-4-hydroxybenzylidene)chroman-4-one ...)
Affinity DataIC50: 4.79E+5nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed