BDBM50341784 CHEMBL1766894::N-(2-(2-phenyl-5-(trifluoromethyl)-1H-imidazole-4-carboxamido)ethyl)-6-(2,2,2-trifluoroethoxy)nicotinamide

SMILES FC(F)(F)COc1ccc(cn1)C(=O)NCCNC(=O)c1[nH]c(nc1C(F)(F)F)-c1ccccc1

InChI Key InChIKey=ISJOQUCYPIZCNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341784   

TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341784(N-(2-(2-phenyl-5-(trifluoromethyl)-1H-imidazole-4-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected Sf9 cells using [14C]oleoyl-CoA after 15 mins by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed