BDBM50342232 CHEMBL1766456::N-(3-Cyanophenyl)-3-(3-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)propanethioamide

SMILES Cc1cccc(n1)-c1nn(CCC(=S)Nc2cccc(c2)C#N)cc1-c1ccc2ncccc2c1

InChI Key InChIKey=HGJGLMBKNFJBHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342232   

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50342232(N-(3-Cyanophenyl)-3-(3-(6-methylpyridin-2-yl)-4-(q...)
Affinity DataIC50: 232nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50342232(N-(3-Cyanophenyl)-3-(3-(6-methylpyridin-2-yl)-4-(q...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed