BDBM50342575 (E)-3-(2-oxopropylidene)-6-(trifluoromethoxy)indolin-2-one::CHEMBL1770397

SMILES CC(=O)C=C1C(=O)Nc2cc(OC(F)(F)F)ccc12

InChI Key InChIKey=MGWOSFBTSQTSCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342575   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342575((E)-3-(2-oxopropylidene)-6-(trifluoromethoxy)indol...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342575((E)-3-(2-oxopropylidene)-6-(trifluoromethoxy)indol...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed