BDBM50342586 (E)-3-(2-(3-aminophenyl)-2-oxoethylidene)-4-chloroindolin-2-one::CHEMBL1770524

SMILES Nc1cccc(c1)C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12

InChI Key InChIKey=YDHKOLZPXCYPMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342586   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342586((E)-3-(2-(3-aminophenyl)-2-oxoethylidene)-4-chloro...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342586((E)-3-(2-(3-aminophenyl)-2-oxoethylidene)-4-chloro...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed