BDBM50342679 CHEMBL1771080::tert-butyl 1'-(6-cyanopyrimidin-4-yl)-4,4'-bipiperidine-1-carboxylate

SMILES CC(C)(C)OC(=O)N1CCC(CC1)C1CCN(CC1)c1cc(ncn1)C#N

InChI Key InChIKey=ULTPMBFRFOMPCB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342679   

LigandPNGBDBM50342679(tert-butyl 1'-(6-cyanopyrimidin-4-yl)-4,4'-bipiper...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342679(tert-butyl 1'-(6-cyanopyrimidin-4-yl)-4,4'-bipiper...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed