BDBM50342700 2-(4-((1R,2S)-2-(2-(4-(1H-1,2,3-triazol-1-yl)phenoxy)ethyl)cyclopropyl)piperidin-1-yl)-5-chloropyrimidine::CHEMBL1771101

SMILES Clc1cnc(nc1)N1CCC(CC1)[C@H]1C[C@H]1CCOc1ccc(cc1)-n1ccnn1

InChI Key InChIKey=XCMQGEUINVIVHT-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342700   

LigandPNGBDBM50342700(2-(4-((1R,2S)-2-(2-(4-(1H-1,2,3-triazol-1-yl)pheno...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342700(2-(4-((1R,2S)-2-(2-(4-(1H-1,2,3-triazol-1-yl)pheno...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50342700(2-(4-((1R,2S)-2-(2-(4-(1H-1,2,3-triazol-1-yl)pheno...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed