BDBM50342926 6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-(thiophen-2-ylmethyl)quinazolin-4-amine::CHEMBL1591577

SMILES CN(Cc1cccs1)c1ncnc2ccc(cc12)-c1ccc2OCOc2c1

InChI Key InChIKey=LXDHFJUOCGKVAV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342926   

TargetDual specificity protein kinase CLK3(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342926(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-(thiophen-...)
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342926(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-(thiophen-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342926(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-(thiophen-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342926(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-(thiophen-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342926(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-(thiophen-...)
Affinity DataIC50: 73nMAssay Description:Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50342926(6-(benzo[d][1,3]dioxol-5-yl)-N-methyl-N-(thiophen-...)
Affinity DataIC50: 173nMAssay Description:Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabeled kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed